Transcripts of cytokeratins as predictors of breast cancer

Cytokeratins (CK) belong to a large family of intermediate filaments that are primarily expressed in epithelial cells and whose members are expressed in various combinations in normal and malignant entities. In breast cancer (BC), keratin typing is a major tool in tumor histodiagnosis, providing molecular parameters to assess its differentiation status. In our study, we evaluated CK5, CK6, CK8, CK14 and CK18 mRNA levels by qPCR, and CK18, CK5...