Are component endpoints equal? A preference study into the practice of composite endpoints in clinical trials

Objectives To examine patients’ perspectives regarding composite endpoints and the utility patients put on possible adverse outcomes of revascularization procedures. Design In the PRECORE study, a stated preference elicitation method Best‐Worst Scaling ( BWS ) was used to determine patient preference for 8 component endpoints ( CE s): need for redo percutaneous coronary intervention ( PCI ) within 1 year, minor stroke with symptoms <24 hours,...