‘Give-up-itis’ revisited: Neuropathology of extremis

Volume: 120, Pages: 14 - 21
Published: Nov 1, 2018
Abstract
The term 'give-up-itis' describes people who respond to traumatic stress by developing extreme apathy, give up hope, relinquish the will to live and die, despite no obvious organic cause. This paper discusses the nature of give-up-itis, with progressive demotivation and executive dysfunction that have clinical analogues suggesting frontal-subcortical circuit dysfunction particularly within the dorsolateral prefrontal and anterior cingulate...
Paper Details
Title
‘Give-up-itis’ revisited: Neuropathology of extremis
Published Date
Nov 1, 2018
Volume
120
Pages
14 - 21
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