Influence of early adalimumab serum levels on immunogenicity and long‐term outcome of anti‐TNF naive Crohn's disease patients: the usefulness of rapid testing

Summary Background Proactive testing of adalimumab serum levels is debated. Aim To study the association between adalimumab serum levels at week 4 and the development of anti‐adalimumab drug antibodies and long‐term outcome in anti‐TNF naive Crohn's disease patients. Methods Serum samples from 116 biologically naive Crohn's disease patients with active disease were prospectively collected at baseline, and weeks 4 and 12. Adalimumab serum levels...