Potential spironolactone effects on collagen metabolism biomarkers in patients with uncontrolled blood pressure
Abstract
An increase in myocardial collagen content may contribute to the development of heart failure; this might be inhibited or reversed by mineralocorticoid receptor antagonists (MRAs). We investigated changes in serum concentrations of the collagen synthesis biomarkers N-terminal propeptide of procollagen type III (PIIINP) (primary outcome) and C-terminal propeptide of procollagen type I (PICP) (secondary outcome) after non-randomised initiation of...
Paper Details
Title
Potential spironolactone effects on collagen metabolism biomarkers in patients with uncontrolled blood pressure
Published Date
Aug 18, 2018
Journal
Volume
105
Issue
4
Pages
307 - 314
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