Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
Abstract
Most older individuals develop inflammageing, a condition characterized by elevated levels of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability, frailty, and premature death. Potential mechanisms of inflammageing include genetic susceptibility, central obesity, increased gut permeability, changes to microbiota composition, cellular senescence, NLRP3 inflammasome activation, oxidative stress caused by...
Paper Details
Title
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
Published Date
Jul 31, 2018
Journal
Volume
15
Issue
9
Pages
505 - 522
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Notes
History