Developmental barcoding of whole mouse via homing CRISPR

Science56.90
Volume: 361, Issue: 6405
Published: Aug 31, 2018
Abstract
INTRODUCTION null The remarkable development of a single cell, the zygote, into the full organism occurs through a complex series of division and differentiation events that resemble a tree, with the zygote at the base branching through lineages that end in the terminal cell types at the top. Characterizing this tree of development has long been a subject of interest, and the combination of modern genome engineering and sequencing technologies...
Paper Details
Title
Developmental barcoding of whole mouse via homing CRISPR
Published Date
Aug 31, 2018
Journal
Volume
361
Issue
6405
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