Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
Abstract
Autophagy is an intracellular bulk degradation process for proteins and organelles. In the heart, autophagy is stimulated by myocardial ischemia. However, the causative role of autophagy in the survival of cardiac myocytes and the underlying signaling mechanisms are poorly understood. Glucose deprivation (GD), which mimics myocardial ischemia, induces autophagy in cultured cardiac myocytes. Survival of cardiac myocytes was decreased by...
Paper Details
Title
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
Published Date
Mar 30, 2007
Journal
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