Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.

Volume: 74, Issue: 8, Pages: 739 - 747
Published: Aug 1, 2018
Abstract
The integral membrane protein zinc metalloprotease ZMPSTE24 possesses a completely novel structure, comprising seven long kinked transmembrane helices that encircle a voluminous 14 000 A3 cavity within the membrane. Functionally conserved soluble zinc metalloprotease residues are contained within this cavity. As part of an effort to understand the structural and functional relationships between ZMPSTE24 and soluble zinc metalloproteases, the...
Paper Details
Title
Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.
Published Date
Aug 1, 2018
Volume
74
Issue
8
Pages
739 - 747
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