Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy.

Volume: 26, Issue: 10, Pages: 2337 - 2356
Published: Oct 3, 2018
Abstract
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by dystrophin gene mutation. Conceptually, replacing the mutated gene with a normal one would cure the disease. However, this task has encountered significant challenges due to the enormous size of the gene and the distribution of muscle throughout the body. The former creates a hurdle for viral vector packaging and the latter begs for whole-body therapy. To address these...
Paper Details
Title
Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy.
Published Date
Oct 3, 2018
Volume
26
Issue
10
Pages
2337 - 2356
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.