Gut Sphingolipid Composition as a Prelude to Necrotizing Enterocolitis
Abstract
Necrotizing enterocolitis (NEC) remains a major challenge in neonatology. Little is known about NEC pathophysiology apart from the presence of pre-event gut dysbiosis. Here, we applied broad range metabolomics to stools obtained 1-5 days before NEC developed from 9 cases (9 samples) and 19 (32 samples) controls matched for gestational age at birth and birth weight. The 764 identified metabolites identified six pathways that differ between cases...
Paper Details
Title
Gut Sphingolipid Composition as a Prelude to Necrotizing Enterocolitis
Published Date
Jul 20, 2018
Journal
Volume
8
Issue
1
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