Combination Antimicrobial Prophylaxis for Hysterectomy: Harm Without the Benefit?

(Abstracted from Am J Obstet Gynecol 2018;218(5):536–537) Results from several studies suggest that prophylactic use of combination antimicrobial regimens reduce postoperative surgical site infections (SSIs) after cesarean delivery and other surgical procedures. A recent study, however, reported that combination regimens were associated with increases in postoperative acute kidney injury (AKI) after nongynecologic surgical...