Cumulative childhood adversity and adult cardiometabolic disease: A meta-analysis.

Adverse childhood experiences may be associated with cardiometabolic morbidity and mortality in adulthood. There is heterogeneity in this literature regarding the type of items in cumulative adversity indices, sample sizes, demographics, and covariates. The present review used quantitative meta-analysis to examine this association and potential moderators.Included studies had a measure of cumulative adversity (an index of at least 2 adverse...