Wild-derived mice: from genetic diversity to variation in immune responses
Abstract
Classical inbred mouse strains have historically been instrumental in mapping immunological traits. However, most of the classical strains originate from a relatively limited number of founder animals, largely within the Mus musculus domesticus subspecies. Therefore, their genetic diversity is ultimately limited. For this reason, it is not feasible to use these mice for exhaustive interrogation of immune signaling pathways. In order to...
Paper Details
Title
Wild-derived mice: from genetic diversity to variation in immune responses
Published Date
Jul 28, 2018
Journal
Volume
29
Issue
7-8
Pages
577 - 584
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History