Plasma urate and risk of Parkinson's disease: A mendelian randomization study
Abstract
Objective Urate is a potent antioxidant, and high plasma urate has been associated with lower incidence of Parkinson's disease (PD) in epidemiological studies. We tested the hypothesis that high concentrations of plasma urate are associated with low incidence of PD. Methods We performed observational and genetic analyses using plasma urate and the urate SLC2A9 rs7442295 and ABCG2 rs2231142 genotype in >102,000 individuals from the CGPS...
Paper Details
Title
Plasma urate and risk of Parkinson's disease: A mendelian randomization study
Published Date
Aug 1, 2018
Journal
Volume
84
Issue
2
Pages
178 - 190
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