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Can Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio at Day +100 be used as a prognostic marker in Multiple Myeloma patients with autologous transplantation?

Published on Sep 1, 2018in Clinical Transplantation 1.67
· DOI :10.1111/ctr.13359
Serife Solmaz Medeni1
Estimated H-index: 1
,
Celal Acar2
Estimated H-index: 2
+ 10 AuthorsGüner Hayri Özsan5
Estimated H-index: 5
(Dokuz Eylül University)
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References26
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Published on Mar 1, 2018in International Journal of Hematology 2.25
Hideto Tamura22
Estimated H-index: 22
(Nippon Medical School)
Despite the advent of novel therapies and improvements in survival, multiple myeloma (MM) remains an incurable disease. Thus, new treatment strategies including immunotherapies are needed for MM patients with stable disease after induction chemotherapy as well as for disease control in patients with advanced disease. However, profound immune dysregulation not only of B cells, but also of other immune cells such as natural killer cells, T cells, and dendritic cells and increase in the number of i...
Published on Feb 9, 2018in Clinical Cancer Research 8.91
Satoshi Takagi9
Estimated H-index: 9
(Harvard University),
Shokichi Tsukamoto2
Estimated H-index: 2
(Harvard University)
+ 14 AuthorsSalomon Manier18
Estimated H-index: 18
(Harvard University)
Purpose: Tumor cell–platelet interactions contribute to tumor progression and metastasis in solid tumors. However, the role of platelets in hematological malignancies is not clear. We investigated the association of platelet activation status with clinical stages in multiple myeloma (MM) patients and explored the role of platelets in MM progression. Experimental Design: Platelets were obtained from healthy donors and MM patients. We examined platelet activation status in MM patients by flow cyto...
Published on Feb 1, 2018in Translational cancer research 1.07
Huaqin Zuo2
Estimated H-index: 2
,
Lili Zhai1
Estimated H-index: 1
+ 2 AuthorsPeipei Xu4
Estimated H-index: 4
Background: Increased neutrophil-to-lymphocyte ratio (NLR) has been proposed to predict poor prognosis in many cancer types. However, the prognostic value of NLR in multiple myeloma (MM) remains largely unknown. This study aimed to investigate whether NLR is an independent predictor of MM. Methods: Data were collected retrospectively from 136 patients who were diagnosed with MM and subjected to bortezomib-thalidomide-dexamethasone chemotherapy at the Nanjing Drum Tower Hospital from 2008 to 2016...
Published on Jan 1, 2018in OncoTargets and Therapy 3.05
Shidai Mu2
Estimated H-index: 2
,
Lisha Ai5
Estimated H-index: 5
+ 2 AuthorsYu Hu13
Estimated H-index: 13
Published on Dec 1, 2017in Breast Cancer Research 5.68
Josee-Lyne Ethier4
Estimated H-index: 4
(U of T: University of Toronto),
Danielle N. Desautels3
Estimated H-index: 3
(Sunnybrook Health Sciences Centre)
+ 2 AuthorsEitan Amir35
Estimated H-index: 35
(U of T: University of Toronto)
Background The presence of a high neutrophil-to-lymphocyte ratio (NLR) has been associated with increased mortality in several malignancies. Here, we quantify the effect of NLR on survival in patients with breast cancer, and examine the effect of clinicopathologic factors on its prognostic value.
Published on Jul 1, 2017in The Korean Journal of Internal Medicine 2.71
Dae Sik Kim6
Estimated H-index: 6
(KU: Korea University),
Eun Sang Yu3
Estimated H-index: 3
(KU: Korea University)
+ 5 AuthorsByung Soo Kim22
Estimated H-index: 22
(KU: Korea University)
Published on Mar 21, 2017in Oncotarget
Lihui Shi5
Estimated H-index: 5
,
Xiaoqi Qin4
Estimated H-index: 4
+ 16 AuthorsPrakrati Acharya4
Estimated H-index: 4
// Lihui Shi 1, * , Xiaoqi Qin 1, 2, * , Huijun Wang 1 , Yonghui Xia 1 , Yuanyuan Li 1 , Xuejing Chen 1 , Lei Shang 1 , Yu-Tzu Tai 3 , Xiaoyan Feng 1 , Prakrati Acharya 4 , Chirag Acharya 3 , Yan Xu 1 , Shuhui Deng 1 , Mu Hao 1 , Dehui Zou 1 , Yaozhong Zhao 1 , Kun Ru 1 , Lugui Qiu 1 , Gang An 1 1 State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China 2 Department of...
Published on Nov 1, 2016in Journal of Clinical Laboratory Analysis 1.73
Supakanya Wongrakpanich2
Estimated H-index: 2
,
Gemlyn George1
Estimated H-index: 1
+ 5 AuthorsGabor Varadi14
Estimated H-index: 14
Object Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are simple, inexpensive prognostic markers for various conditions. The objective of this study was to determine the prognostic significance of NLR and PLR in patients with multiple myeloma (MM) in terms of survival. Method A retrospective chart review study was conducted for 175 patients who met the criterion of diagnosis for MM between January 2004 and September 2014. Result The median age of diagnosis was 69 yea...
Published on Sep 1, 2016in Medicine 1.87
Jing Wang1
Estimated H-index: 1
,
Min Zhou1
Estimated H-index: 1
+ 5 AuthorsJian Ouyang1
Estimated H-index: 1
This study aims to investigate whether neutrophil to lymphocyte ratio (NLR) is an independent predictor in newly diagnosed diffuse large B-cell lymphoma (DLBCL) patients in the rituximab era. Data from newly diagnosed DLBCL patients at Nanjing Drum Tower Hospital from 2006 to 2015 were retrospectively reviewed. We used the receiver operating characteristic (ROC) curve analysis to generate the optimal cutoff value for NLR. Among those 156 patients enrolled, the NLR was < 3.0 in 46.8% (73/156) of ...
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