Interplay between NRF1, E2F4 and MYC transcription factors regulating common target genes contributes to cancer development and progression

Volume: 41, Issue: 5, Pages: 465 - 484
Published: Jul 25, 2018
Abstract
Nuclear respiratory factor 1 (NRF1), historically perceived as a protein regulating genes controlling mitochondrial biogenesis, is now widely recognized as a multifunctional protein and as a key player in the transcriptional modulation of genes implicated in various cellular functions. Here, we present emerging data supporting novel roles of NRF1 in cancer development and progression through its interplay with the transcription factors E2F4 and...
Paper Details
Title
Interplay between NRF1, E2F4 and MYC transcription factors regulating common target genes contributes to cancer development and progression
Published Date
Jul 25, 2018
Volume
41
Issue
5
Pages
465 - 484
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