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Diarylheptanoids from the root of Curcuma aromatica and their antioxidative effects

Published on Oct 1, 2018in Phytochemistry Letters1.34
· DOI :10.1016/j.phytol.2018.07.021
Shengjuan Dong2
Estimated H-index: 2
(Kunming University of Science and Technology),
Xiaodong Luo1
Estimated H-index: 1
(CAS: Chinese Academy of Sciences)
+ 3 AuthorsWeifeng Dai4
Estimated H-index: 4
(Kunming University of Science and Technology)
Abstract
Four rare diarylheptanoids containing tetrahydropyran moieties (1-4) and five known diarylheptanoids (6-10) were isolated from the n-BuOH fraction of 75% ethanol extract from the root of Curcuma aromatica, along with a new phenol (5). Their planar and stereochemical structures were established using HRESIMS and spectroscopic methods, including ECD data. All compounds (1-10) exhibited antioxidant effects on the model of H2O2-induced damage in PC12 cell at their dosages of 10 mu M, while compounds 1, 3, 6, 7, 9 and 10 produced that effects at 1 mu M (P < 0.001).
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  • Citations (2)
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