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Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements

Published on Jul 16, 2018in Nature Biotechnology31.86
· DOI :10.1038/nbt.4192
Michael Kosicki2
Estimated H-index: 2
,
Kärt Tomberg5
Estimated H-index: 5
,
Allan Bradley112
Estimated H-index: 112
Abstract
Cas9-induced double stranded breaks can cause large deletions near the target site and more complex genomic rearrangements in mouse and human stem cells.
  • References (38)
  • Citations (169)
References38
Newest
#1Katharina Boroviak (Wellcome Trust Sanger Institute)H-Index: 5
#2Beiyuan Fu (Wellcome Trust Sanger Institute)H-Index: 26
Last.Allan Bradley (Wellcome Trust Sanger Institute)H-Index: 112
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#1Supriya Sinha (University of Texas Health Science Center at San Antonio)H-Index: 2
#2Fuyang LiH-Index: 16
Last.Sang Eun LeeH-Index: 31
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#1Tatjana I. Cornu (University of Freiburg)H-Index: 2
#2Claudio Mussolino (University of Freiburg)H-Index: 15
Last.Toni Cathomen (University of Freiburg)H-Index: 38
view all 3 authors...
#1Megan Van Overbeek (University of California, Berkeley)H-Index: 1
#2Daniel Capurso (University of California, Berkeley)H-Index: 2
Last.Bastien Vidal (University of California, Berkeley)H-Index: 2
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#1Katharina Boroviak (Wellcome Trust Sanger Institute)H-Index: 5
#2Brendan Doe (Wellcome Trust Sanger Institute)H-Index: 9
Last.Allan Bradley (Wellcome Trust Sanger Institute)H-Index: 112
view all 5 authors...
#1Benjamin P. Kleinstiver (Harvard University)H-Index: 14
#2Vikram Pattanayak (Harvard University)H-Index: 11
Last.J. Keith Joung (Harvard University)H-Index: 60
view all 7 authors...
#1Ian SlaymakerH-Index: 9
#2Linyi Gao (MIT: Massachusetts Institute of Technology)H-Index: 6
Last.Feng ZhangH-Index: 104
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Cited By169
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#1Xiaolu Zhang (Science for Life Laboratory)
#2Silvano Garnerone (Science for Life Laboratory)H-Index: 9
Last.Caterina Marchiò (UNITO: University of Turin)H-Index: 30
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#1Alba Carreras (Sahlgrenska University Hospital)H-Index: 2
#2Alba Carreras (Sahlgrenska University Hospital)H-Index: 1
Last.Mikael BjursellH-Index: 19
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#1Keith Sabin (UMN: University of Minnesota)H-Index: 2
#2Peng Jiang (Morgridge Institute for Research)H-Index: 4
Last.Karen Echeverri (UMN: University of Minnesota)H-Index: 11
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#1Yang Wang (DI: Discovery Institute)H-Index: 3
#2Yang Wang (DI: Discovery Institute)
Last.Jing Crystal Zhao (DI: Discovery Institute)
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#1Dimitre R. SimeonovH-Index: 12
#2Alexander Brandt (University of California, Berkeley)H-Index: 2
Last.Claudia M.B. Carvalho (BCM: Baylor College of Medicine)H-Index: 22
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