Transcriptome Analyses Reveal Adult Metabolic Syndrome With Intrauterine Growth Restriction in Pig Models

Epidemiological data has indicated that intrauterine growth retardation (IUGR) is a risk factor for adult metabolic syndrome. However, the causative genetic mechanism leading to the phenotype in adulthood has not been well characterized. In the present study, normal and IUGR adult pigs were used as a model system to survey differences in global gene expression in livers through transcriptome sequencing. The transcriptome libraries generated...