Original paper
Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease
Abstract
Observational studies have shown that increased plasma urate is associated with lower risk of Parkinson's disease (PD), but these studies were not designed to test causality. If a causal relationship exists, then modulating plasma urate levels could be a potential preventive avenue for PD. We used a large two-sample Mendelian randomization (MR) design to assess for a causal relationship between plasma urate and PD risk.We used a genetic...
Paper Details
Title
Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease
Published Date
Aug 1, 2018
Journal
Volume
84
Issue
2
Pages
191 - 199
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Notes
History