Whole-genome amplification in double-digest RADseq results in adequate libraries but fewer sequenced loci

PeerJ2.70
Volume: 6, Pages: e5089 - e5089
Published: Jul 17, 2018
Abstract
Whole-genome amplification by multiple displacement amplification (MDA) is a promising technique to enable the use of samples with only limited amount of DNA for the construction of RAD-seq libraries. Previous work has shown that, when the amount of DNA used in the MDA reaction is large, double-digest RAD-seq (ddRAD) libraries prepared with amplified genomic DNA result in data that are indistinguishable from libraries prepared directly from...
Paper Details
Title
Whole-genome amplification in double-digest RADseq results in adequate libraries but fewer sequenced loci
Published Date
Jul 17, 2018
Journal
Volume
6
Pages
e5089 - e5089
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