Gas-phase protomers of p -(dimethylamino)chalcone investigated by travelling-wave ion mobility mass spectrometry (TWIMS)

Results from ion‐mobility (IM) separation experiments demonstrate that O ‐ and N ‐protomers of p ‐(dimethylamino)chalcone ( p ‐DMAC) can coexist in the gas phase. The relative populations of the two protomers strongly depend on the ion‐generating settings and the conditions the precursor ions experience from the point of their gas‐phase inception to the time of their detection. Under relatively dry source conditions, the ratio of the gas‐phase...