Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring
Abstract
Recent research has focused on environmental effects that control tissue functionality and systemic metabolism. However, whether such stimuli affect human thermogenesis and body mass index (BMI) has not been explored. Here we show retrospectively that the presence of brown adipose tissue (BAT) and the season of conception are linked to BMI in humans. In mice, we demonstrate that cold exposure (CE) of males, but not females, before mating results...
Paper Details
Title
Cold-induced epigenetic programming of the sperm enhances brown adipose tissue activity in the offspring
Published Date
Jul 9, 2018
Journal
Volume
24
Issue
9
Pages
1372 - 1383
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