A Canadian Cost-Utility Analysis of two Trabecular Micro-Bypass Stents in Patients with Mild-to-Moderate Open-Angle Glaucoma

To estimate the cost-utility of two micro-bypass trabecular stents (MBTS) implantation versus standard of care (SOC) in the Canadian healthcare setting. A Markov model was designed to track progression of glaucoma through health states defined using Hodapp-Parrish-Anderson stages and death: mild, moderate, advanced, severe/blind glaucoma over a 15 year time horizon. Reduction in intraocular pressure (IOP) and medication use due to MBTS and SOC...