In-silico studies of some oxadiazoles derivatives as anti-diabetic compounds

An in-silico study was performed to investigate the anti-diabetic activities of 27 Oxadiazoles derivatives. The anti-diabetic compounds were optimized using Density Functional Theory (DFT) method utilizing B3LYP version with 6-31G∗ basis set. Genetic Function Algorithm (GFA) was used to build four models. Model 1 was chosen as the best model, assessed and found to be statistically significant with LOF = 0.030552, R2 = 0.9681, R2adj = 0.9567,...