MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.
Abstract
Micropeptide regulator of β-oxidation (MOXI) is a conserved muscle-enriched protein encoded by an RNA transcript misannotated as non-coding. MOXI localizes to the inner mitochondrial membrane where it associates with the mitochondrial trifunctional protein, an enzyme complex that plays a critical role in fatty acid β-oxidation. Isolated heart and skeletal muscle mitochondria from MOXI knockout mice exhibit a diminished ability to metabolize...
Paper Details
Title
MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.
Published Date
Jun 26, 2018
Journal
Volume
23
Issue
13
Pages
3701 - 3709
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Notes
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