Immuno-monitoring reveals an extended subclinical disease activity in tocilizumab-treated giant cell arteritis

Tocilizumab is effective in inducing and maintaining remission of GCA. Despite clinical and serological control of disease, magnetic resonance angiography may show persistence of inflammatory signals of unknown significance in arterial walls. Thus, there is an unmet need for tools to detect subclinical disease activity.Immune-inflammatory markers were measured in prospectively collected sera of the first randomized, double-blind,...