Review paper
Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
Abstract
Although T lymphocytes have long been appreciated for their role in the immunosurveillance of cancer, it has been the realization that cancer cells may ultimately escape a response from tumor-reactive T cells that has ignited efforts to enhance the efficacy of anti-tumor immune responses. Recent advances in our understanding of T cell immunobiology have been particularly instrumental in informing therapeutic strategies to overcome mechanisms of...
Paper Details
Title
Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
Published Date
Sep 1, 2018
Volume
62
Pages
29 - 39
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