Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells

Volume: 96, Issue: 10, Pages: 1104 - 1119
Published: Aug 10, 2018
Abstract
Current influenza A virus (IAV) vaccines stimulate antibody responses that are directed against variable regions of the virus, and are therefore ineffective against divergent strains. As CD8+ T cells target the highly conserved, internal IAV proteins, they have the potential to increase heterosubtypic immunity. Early T-cell priming events influence lasting memory, which is required for long-term protection. However, the early responding,...
Paper Details
Title
Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells
Published Date
Aug 10, 2018
Volume
96
Issue
10
Pages
1104 - 1119
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