UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma

Summary Previously, we identified UBE 2L3 as a susceptibility gene for chronic hepatitis B virus ( HBV ) infection through genome‐wide association study. Here, we analysed the association between genetic variants of UBE 2L3 and the susceptibility to HBV ‐related hepatocellular carcinoma ( HCC ) and further explored its role in HCC . This case‐control study included 1344 subjects who cleared HBV , 1560 HBV carriers and 1057 HBV‐related HCC...