Microfluidics: Tuning Enzymatically Crosslinked Silk Fibroin Hydrogel Properties for the Development of a Colorectal Cancer Extravasation 3D Model on a Chip (Global Challenges 5-6/2018)

In order to win the battle against cancer, further advances are needed to unveil identification of cancer-causing agents in in vitro and in vivo animal models, as well as for the development of personalized therapies and drug screening. They provide insightful knowledge on the mechanisms of tumor growth and metastasis. Therefore, the transition from 2D to 3D models, comprising the integration of tissue engineering (TE) strategies with...