Four and a half LIM domain protein signaling and cardiomyopathy
Abstract
Four and a half LIM domain (FHL) protein family members, FHL1 and FHL2, are multifunctional proteins that are enriched in cardiac muscle. Although they both localize within the cardiomyocyte sarcomere (titin N2B), they have been shown to have important yet unique functions within the context of cardiac hypertrophy and disease. Studies in FHL1-deficient mice have primarily uncovered mitogen-activated protein kinase (MAPK) scaffolding functions...
Paper Details
Title
Four and a half LIM domain protein signaling and cardiomyopathy
Published Date
Jun 20, 2018
Journal
Volume
10
Issue
4
Pages
1073 - 1085
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