Targeting dendritic cells in pancreatic ductal adenocarcinoma
Abstract
Dendritic cells (DC) are an integral part of the tumor microenvironment. Pancreatic cancer is characterized by reduced number and function of DCs, which impacts antigen presentation and contributes to immune tolerance. Recent data suggest that exosomes can mediate communication between pancreatic cancer cells and DCs. Furthermore, levels of DCs may serve as prognostic factors. There is also growing evidence for the effectiveness of vaccination...
Paper Details
Title
Targeting dendritic cells in pancreatic ductal adenocarcinoma
Published Date
Jun 18, 2018
Journal
Volume
18
Issue
1
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