Baseline Predictors and Influence of Early Weight Loss during an Intensive Weight Management Programme on Remission of Type 2 Diabetes after 12 Months—Post-Hoc Analysis of the Diabetes Remission Clinical Trial (DiRECT)

Introduction: An intensive weight management programme (Counterweight-Plus), including low-energy formula diet for up to 16 weeks, then a structured approach for weight-loss maintenance, delivered within routine primary care, has shown striking remissions of type 2 diabetes (T2DM diagnosis <6 years). Remissions at 12 months were achieved by 46% overall, by 73% with weight loss >10kg. Methods: Baseline factors, and weight losses of...