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Functional characterization of CYP4G11—a highly conserved enzyme in the western honey bee Apis mellifera

Published on Oct 1, 2018in Insect Molecular Biology2.44
· DOI :10.1111/imb.12516
Bernarda Calla11
Estimated H-index: 11
(UIUC: University of Illinois at Urbana–Champaign),
Marina MacLean3
Estimated H-index: 3
(UNR: University of Nevada, Reno)
+ 4 AuthorsMay R. Berenbaum67
Estimated H-index: 67
(UIUC: University of Illinois at Urbana–Champaign)
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  • References (59)
  • Citations (2)
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References59
Newest
Published on Feb 1, 2018in Molecular Genetics and Genomics2.88
Hongyi Nie3
Estimated H-index: 3
(Fujian Agriculture and Forestry University),
Shupeng Xu1
Estimated H-index: 1
(Fujian Agriculture and Forestry University)
+ 7 AuthorsSongkun Su3
Estimated H-index: 3
(Fujian Agriculture and Forestry University)
Honey bee is a social insect. Its colony is mainly coordinated by the chemical signals such as pheromones produced by queen or brood. Correspondingly, the worker bee developed numerous complicated olfactory sensilla in antennae for detection of these colony chemical signals and nectar/pollen signals in foraging. With the normal development of new emerged workers, young adults (nurse bee) worked in colony at the first 2–3 weeks and then followed by the foraging activity outside of the hive, which...
Published on Sep 1, 2017in Insect Biochemistry and Molecular Biology3.62
Ming-Cheng Wu1
Estimated H-index: 1
(NTU: National Taiwan University),
Yu-Wen Chang1
Estimated H-index: 1
(NTU: National Taiwan University)
+ 1 AuthorsEn-Cheng Yang19
Estimated H-index: 19
(NTU: National Taiwan University)
Abstract Honey bee larvae exposed to sublethal doses of imidacloprid show behavioural abnormalities as adult insects. Previous studies have demonstrated that this phenomenon originates from abnormal neural development in response to imidacloprid exposure. Here, we further investigated the global gene expression changes in the heads of newly emerged adults and observed that 578 genes showed more than 2-fold changes in gene expression after imidacloprid exposure. This information might aid in unde...
Published on May 25, 2017in Insects
Michael E. Sparks5
Estimated H-index: 5
(USDA: United States Department of Agriculture),
Joshua H. Rhoades1
Estimated H-index: 1
(USDA: United States Department of Agriculture)
+ 6 AuthorsDawn E. Gundersen-Rindal10
Estimated H-index: 10
(USDA: United States Department of Agriculture)
The harlequin bug, Murgantia histrionica (Hahn), is an agricultural pest in the continental United States, particularly in southern states. Reliable gene sequence data are especially useful to the development of species-specific, environmentally friendly molecular biopesticides and effective biolures for this insect. Here, mRNAs were sampled from whole insects at the 2nd and 4th nymphal instars, as well as sexed adults, and sequenced using Illumina RNA-Seq technology. A global assembly of these ...
Wenfu Mao13
Estimated H-index: 13
(UIUC: University of Illinois at Urbana–Champaign),
Mary A. Schuler54
Estimated H-index: 54
(UIUC: University of Illinois at Urbana–Champaign),
May R. Berenbaum67
Estimated H-index: 67
(UIUC: University of Illinois at Urbana–Champaign)
Cytochrome P450 monooxygenases (P450) in the honey bee, Apis mellifera , detoxify phytochemicals in honey and pollen. The flavonol quercetin is found ubiquitously and abundantly in pollen and frequently at lower concentrations in honey. Worker jelly consumed during the first 3 d of larval development typically contains flavonols at very low levels, however. RNA-Seq analysis of gene expression in neonates reared for three days on diets with and without quercetin revealed that, in addition to up-r...
Published on Jan 30, 2017in Genome Biology and Evolution3.73
Panagiotis Ioannidis13
Estimated H-index: 13
(Swiss Institute of Bioinformatics),
Felipe A. Simão8
Estimated H-index: 8
(Swiss Institute of Bioinformatics)
+ 6 AuthorsEvgeny M. Zdobnov55
Estimated H-index: 55
(Swiss Institute of Bioinformatics)
Insects comprise the most diverse and successful animal group with over one million described species that are found in almost every terrestrial and limnic habitat, with many being used as important models in genetics, ecology, and evolutionary research. Genome sequencing projects have greatly expanded the sampling of species from many insect orders, but genomic resources for species of certain insect lineages have remained relatively limited to date. To address this paucity, we sequenced the ge...
Published on Dec 1, 2016in BMC Genomics3.50
Alfredo Rago4
Estimated H-index: 4
(University of Birmingham),
Donald G. Gilbert12
Estimated H-index: 12
(IU: Indiana University)
+ 5 AuthorsJohn K. Colbourne42
Estimated H-index: 42
(University of Birmingham)
Background Nasonia vitripennis is an emerging insect model system with haplodiploid genetics. It holds a key position within the insect phylogeny for comparative, evolutionary and behavioral genetic studies. The draft genomes for N. vitripennis and two sibling species were published in 2010, yet a considerable amount of transcriptiome data have since been produced thereby enabling improvements to the original (OGS1.2) annotated gene set. We describe and apply the EvidentialGene method used to pr...
Published on Sep 1, 2016in Insect Biochemistry and Molecular Biology3.62
Nan Chen3
Estimated H-index: 3
(NWAFU: Northwest A&F University),
Yongliang Fan15
Estimated H-index: 15
(NWAFU: Northwest A&F University)
+ 3 AuthorsTong-Xian Liu1
Estimated H-index: 1
(NWAFU: Northwest A&F University)
Terrestrial insects deposit a layer of hydrocarbons (HCs) as waterproofing agents on their epicuticle. The insect-specific CYP4G genes, subfamily members of P450, have been found in all insects with sequenced genomes to date. They are critical for HC biosynthesis in Drosophila; however, their functional roles in other insects including the piercing-sucking hemipterous aphids remain unknown. In this study, we presented the molecular characterization and a functional study of the CYP4G51 gene in t...
Vasileia Balabanidou4
Estimated H-index: 4
(FORTH: Foundation for Research & Technology – Hellas),
Anastasia Kampouraki4
Estimated H-index: 4
(UoC: University of Crete)
+ 12 AuthorsAmy Lynd11
Estimated H-index: 11
(LSTM: Liverpool School of Tropical Medicine)
The role of cuticle changes in insecticide resistance in the major malaria vector Anopheles gambiae was assessed. The rate of internalization of (14)C deltamethrin was significantly slower in a resistant strain than in a susceptible strain. Topical application of an acetone insecticide formulation to circumvent lipid-based uptake barriers decreased the resistance ratio by ∼50%. Cuticle analysis by electron microscopy and characterization of lipid extracts indicated that resistant mosquitoes had ...
Published on Jul 1, 2016in Scientific Reports4.01
Zhitao Yu4
Estimated H-index: 4
,
Xueyao Zhang8
Estimated H-index: 8
+ 5 AuthorsJianzhen Zhang21
Estimated H-index: 21
Citation: Yu, Z. T., Zhang, X. Y., Wang, Y. W., Moussian, B., Zhu, K. Y., Li, S., . . . Zhang, J. Z. (2016). LmCYP4G102: An oenocyte-specific cytochrome P450 gene required for cuticular waterproofing in the migratory locust, Locusta migratoria. Scientific Reports, 6, 11. doi:10.1038/srep29980
Published on Dec 1, 2015in BMC Genomics3.50
D. J. Park7
Estimated H-index: 7
(SNU: Seoul National University),
Je Won Jung11
Estimated H-index: 11
(SNU: Seoul National University)
+ 12 AuthorsYoonseong Park32
Estimated H-index: 32
(KSU: Kansas State University)
Background The honey bee is an important model system for increasing understanding of molecular and neural mechanisms underlying social behaviors relevant to the agricultural industry and basic science. The western honey bee, Apis mellifera, has served as a model species, and its genome sequence has been published. In contrast, the genome of the Asian honey bee, Apis cerana, has not yet been sequenced. A. cerana has been raised in Asian countries for thousands of years and has brought considerab...
Cited By2
Newest
Published in bioRxiv
Amy Lynd11
Estimated H-index: 11
(LSTM: Liverpool School of Tropical Medicine),
Vasileia Balabanidou4
Estimated H-index: 4
(FORTH: Foundation for Research & Technology – Hellas)
+ -3 AuthorsGareth Lycett14
Estimated H-index: 14
(LSTM: Liverpool School of Tropical Medicine)
Oenocytes are an insect cell type having diverse physiological functions ranging from cuticular hydrocarbon (CHC) production to insecticide detoxification that may impact their capacity to transmit pathogens. To develop functional genetic tools to study Anopheles gambiae oenocytes, we have trapped an oenocyte enhancer to create a transgenic mosquito Gal4 driver line that mediates tissue-specific expression. After crossing with UAS-reporter lines, An. gambiae oenocytes are fluorescently tagged th...
Published on Jul 1, 2019in Insect Biochemistry and Molecular Biology3.62
Mary Kefi1
Estimated H-index: 1
,
Vasileia Balabanidou4
Estimated H-index: 4
+ 3 AuthorsJohn Vontas39
Estimated H-index: 39
Abstract Cuticular hydrocarbon (CHC) biosynthesis is a major pathway of insect physiology. In Drosophila melanogaster the cytochrome P450 CYP4G1 catalyses the insect-specific oxidative decarbonylation step, while in the malaria vector Anopheles gambiae , two CYP4G paralogues, CYP4G16 and CYP4G17 are present. Analysis of the subcellular localization of CYP4G17 and CYP4G16 in larval and pupal stages revealed that CYP4G16 preserves its PM localization across developmental stages analyzed; however C...
Published on Nov 1, 2018in Insect Biochemistry and Molecular Biology3.62
Marina MacLean3
Estimated H-index: 3
(UNR: University of Nevada, Reno),
Jeffrey Nadeau3
Estimated H-index: 3
(UNR: University of Nevada, Reno)
+ 2 AuthorsGary J. Blomquist49
Estimated H-index: 49
(UNR: University of Nevada, Reno)
Abstract Hydrocarbon biosynthesis in insects involves the elongation of fatty acyl-CoAs to very-long chain fatty acyl-CoAs that are then reduced and converted to hydrocarbon, with the last step involving the oxidative decarbonylation of an aldehyde to hydrocarbon and carbon dioxide. Cytochromes P450 in the 4G family decarbonylate aldehydes to hydrocarbon. All insect acyl-CoA reductases studied to date reduce fatty acyl-CoAs to alcohols. The results of the work reported herein demonstrate that CY...