A Retinoic Acidβ2-Receptor Agonist Exerts Cardioprotective Effects

Volume: 366, Issue: 2, Pages: 314 - 321
Published: Jun 15, 2018
Abstract
We previously discovered that oral treatment with AC261066, a synthetic selective agonist for the retinoic acid β2-receptor, decreases oxidative stress in the liver, pancreas, and kidney of mice fed a high-fat diet (HFD). Since hyperlipidemic states are causally associated with myocardial ischemia and oxidative stress, we have now investigated the effects of AC261066 in an ex vivo ischemia/reperfusion (I/R) injury model in...
Paper Details
Title
A Retinoic Acidβ2-Receptor Agonist Exerts Cardioprotective Effects
Published Date
Jun 15, 2018
Volume
366
Issue
2
Pages
314 - 321
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