Ribosome recycling is coordinated by processive events in two asymmetric ATP sites of ABCE1

Volume: 1, Issue: 3, Pages: e201800095 - e201800095
Published: Jun 1, 2018
Abstract
Ribosome recycling orchestrated by ABCE1 is a fundamental process in protein translation and mRNA surveillance, connecting termination with initiation. Beyond the plenitude of well-studied translational GTPases, ABCE1 is the only essential factor energized by ATP, delivering the energy for ribosome splitting via two nucleotide-binding sites by a yet unknown mechanism. Here, we define how allosterically coupled ATP binding and hydrolysis events...
Paper Details
Title
Ribosome recycling is coordinated by processive events in two asymmetric ATP sites of ABCE1
Published Date
Jun 1, 2018
Volume
1
Issue
3
Pages
e201800095 - e201800095
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