Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells
Abstract
Osteoarthritis (OA) is a widespread arthritic disease and a primary cause of disability. Increasing evidence suggests that inflammation has a pivotal part in its pathogenesis. Interleukin-1β (IL-1β) is a primary mediator of local inflammatory processes in OA. Current therapies for OA mainly focus on the symptoms of the advanced stage of the disease. The possible utilization of bone marrow mesenchymal stem cells (BMSCs) to regenerate cartilage is...
Paper Details
Title
Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells
Published Date
Jun 14, 2018
Journal
Volume
9
Issue
1
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