Pharmacodynamics of regulatory T cells in mice and humans treated with low-dose IL-2
Volume: 142, Issue: 4, Pages: 1344 - 1346.e3
Published: Oct 1, 2018
Abstract
IL-2 is the major cytokine controlling homeostasis and function of regulatory T (Treg) cells.1Malek T.R. Castro I. Interleukin-2 receptor signaling: at the iterface between tolerance and immunity.Immunity. 2010; 33: 153-165Abstract Full Text Full Text PDF PubMed Scopus (536) Google Scholar At low dose, IL-2 specifically activates Treg cells and improves autoimmunity in mice and humans.2Klatzmann D. Abbas A.K. The promise of low-dose...
Paper Details
Title
Pharmacodynamics of regulatory T cells in mice and humans treated with low-dose IL-2
Published Date
Oct 1, 2018
Volume
142
Issue
4
Pages
1344 - 1346.e3
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