Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome
Abstract
Atypical hemolytic uremic syndrome (aHUS) is a rare, genetic, life-threatening disease. The Global aHUS Registry collects real-world data on the natural history of the disease. Here we characterize end-stage renal disease (ESRD)-free survival, the rate of thrombotic microangiopathy, organ involvement and the genetic background of 851 patients in the registry, prior to eculizumab treatment. A sex-specific difference was apparent according to age...
Paper Details
Title
Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome
Published Date
Aug 1, 2018
Journal
Volume
94
Issue
2
Pages
408 - 418
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