Original paper
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes
Abstract
Chemerin is a recently discovered adipokine shown to be involved in both inflammatory and metabolic processes. Here, we demonstrate that chemerin serum levels are elevated in patients with multiple myeloma and that it increases with disease progression. We found that chemerin is expressed by stromal cells and preadipocytes, whereas its receptor CCRL2 is expressed by primary myeloma cells, suggesting a paracrine signaling loop between bone marrow...
Paper Details
Title
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes
Published Date
Jun 14, 2018
Journal
Volume
6
Issue
1
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Notes
History