Amino Acid Signature in Human Melanoma Cell Lines from Different Disease Stages
Abstract
Cancer cells rewire metabolism to sustain high proliferation rates. Beside glycolysis and glutaminolysis, amino acids substitute as energy source, feed fatty acid biosynthesis and represent part of the secretome of transformed cells, including melanoma. We have therefore investigated acetate, pyruvate and the amino acid composition of the secretome of human melanoma cells representing the early slow (WM35, WM278, WM793b and VM21) and metastatic...
Paper Details
Title
Amino Acid Signature in Human Melanoma Cell Lines from Different Disease Stages
Published Date
Apr 19, 2018
Journal
Volume
8
Issue
1
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