Acute and Chronic Resistance-Training Downregulates Select Line-1 Retrotransposon Activity Markers in Human Skeletal Muscle

Transposable elements or “jumping genes” are mobile genetic elements with the ability to amplify themselves within the genome. This gene mobility lends itself to the possibility of mutagenesis within cells, which is further compounded by the fact that these elements constitute ~50% our genome. Transposable elements, most notably LINE- 1, have important implications for both gene regulation and gene expression under a variety of conditions....