Radioprotective Effect of Cerium Oxide Nanoparticles Against Genotoxicity Induced by Ionizing Radiation on Human Lymphocytes

Background: Ionizing radiation induces DNA damage on normal cell results in apoptosis and cell deaths. Objectives: The radioprotective effects of cerium oxide nanoparticles (CNPs) on genotoxicity, apoptosis and necrosis induced by Ionizing Radiation (IR) in human healthy lymphocytes as highly radiosensitive cells were investigated. Materials and Methods: Lymphocytes were prepared from three volunteers and then treated with CNPs at different...