MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series

Volume: 35, Issue: 8, Pages: 1431 - 1435
Published: Jun 7, 2018
Abstract
To evaluate the possibility of correcting metabolic defects in gametes and embryos due to methylene tetra hydrofolate reductase (MTHFR) isoforms C677T and A1298C, by supplementation with 5-methyl THF instead of synthetic folic acid. In these couples, high doses of folic acid lead to UMFA (un-metabolized folic acid) syndrome. Thirty couples with fertility problems lasting for at least 4 years, such as recurrent fetal loss, premature ovarian...
Paper Details
Title
MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series
Published Date
Jun 7, 2018
Volume
35
Issue
8
Pages
1431 - 1435
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