Inhibition of Mast Cell Function and Proliferation by mTOR Activator MHY1485
Abstract
Mast cells integrate innate and adaptive immunity and are implicated in pathophysiological conditions, including allergy, asthma, and anaphylaxis. Cross-linking of the high-affinity IgE receptor (FcεRI) initiates diverse signal transduction pathways and induces release of proinflammatory mediators by mast cells. In this study, we demonstrated that hyperactivation of mechanistic target of rapamycin (mTOR) signaling using the mTOR activator...
Paper Details
Title
Inhibition of Mast Cell Function and Proliferation by mTOR Activator MHY1485
Published Date
Jan 1, 2018
Journal
Volume
18
Issue
3
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Notes
History