Multiple Functions of Cellular FLIP Are Essential for Replication of Hepatitis B Virus

Volume: 92, Issue: 16
Published: Aug 15, 2018
Abstract
Although the chronic hepatitis B virus (HBV) infection still poses a major health concern, the host factors which are required for the replication of HBV are largely uncharacterized. Our studies identify cellular FLICE inhibitory protein (c-FLIP) as an essential factor in HBV replication. We found the dual roles of c-FLIP in regulation of HBV replication: c-FLIP interacts with HBx and enhances its stability and regulates the expression or...
Paper Details
Title
Multiple Functions of Cellular FLIP Are Essential for Replication of Hepatitis B Virus
Published Date
Aug 15, 2018
Volume
92
Issue
16
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