Gender-dependent changes in physical development, BDNF content and GSH redox system in a model of acute neonatal hypoxia in rats
Abstract
Perinatal hypoxia-ischaemia is one of the leading factors that negatively influence the development of the central nervous system. Our aim was to investigate the effects of sex on the outcomes of acute neonatal hypoxia (ANH) in rat pups. Male and female Wistar rats were exposed to a hypoxic condition (8% oxygen for 120 min) at postnatal day 2 (P2). Immediately after ANH an increase in HIF1-α gene expression was observed in the rat brains,...
Paper Details
Title
Gender-dependent changes in physical development, BDNF content and GSH redox system in a model of acute neonatal hypoxia in rats
Published Date
Sep 1, 2018
Journal
Volume
350
Pages
87 - 98
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