Resveratrol counteracts inflammation more efficiently than the drug 5-aminosalicylic acid in cytokine-stimulated human intestinal cells

Dietary polyphenols have been considered as a valuable strategy to combat chronic disorders, such as Inflammatory Bowel Disease (IBD). The aim of this study was to scrutinize the biochemical mechanisms behind the anti-inflammatory effects of a well-known polyphenol, Resveratrol (Resv), comparing them to those of a first-line therapy for IBD, the 5 aminosalicylic acid (5 ASA), using a human intestinal cell line (HT 29). In cytokine-treated cells,...